Coronary artery disease diagnosis by means of heart rate variability analysis using respiratory information

Autores

Hernando, D; Kahonen, M; Lazaro, J; Lehtinen, R; Nieminen, T; Nikus, K; Lehtimaki, T; Bailon, R; Viik, J

Revista

EMBEC & NBC 2017

Año: 2018 Volumen: 65 Páginas: 270-273

Editor:

SPRINGER-VERLAG SINGAPORE PTE LTD

DOI:

10.1007/978-981-10-5122-7\_68

Organización:

Univ Tampere, BioMediTech Inst; Tampere Univ Technol, BioMediTech Inst; Finnish Soc Med Phys & Med Engn; Int Org Med & Biol Engn; European Alliance Med & Biol Engn & Sci; EMBEC Soc

Resumen

Heart rate variability (HRV) analysis during exercise has been used to evaluate cardiovascular response to the stress of exercise, which may offer additional value than in rest condition. To properly analyze HRV during exercise, several challenges need to be addressed, such as including respiratory information and removing the dependance with the mean heart rate (HR) level. The objective of this work is to extract parameters from HRV analysis and respiratory information during exercise to evaluate their capability of diagnose coronary artery disease (CAD). Significant differences in mean HR were found due to medication effect in patients with CAD. By correcting the HRV parameters by mean HR, this effect is minimized. Power related to high frequency, when guided by respiration, results to have the best diagnosis capability (AUC > 0.7).

Palabras clave

Exercise ; test ; respiratory ; rate ; CAD ; diagnosis

Afiliación

Hernando, D (Reprint Author), Univ Zaragoza, IIS Aragon, BSICoS Grp, I3A, Zaragoza, Spain.
Hernando, D (Reprint Author), CIBER, Madrid, Spain.
Hernando, D.; Bailon, R., Univ Zaragoza, IIS Aragon, BSICoS Grp, I3A, Zaragoza, Spain.
Hernando, D.; Bailon, R., CIBER, Madrid, Spain.
Kahonen, M., Tampere Univ Hosp, Dept Clin Physiol, Tampere, Finland.
Kahonen, M.; Nikus, K.; Lehtimaki, T., Univ Tampere, Fac Med & Life Sci, Tampere, Finland.
Lazaro, J., Katholieke Univ Leuven, ESAT, STADIUS, Leuven, Belgium.
Lazaro, J., IMEC, Leuven, Belgium.
Lehtinen, R., Tampere Univ Appl Sci, Tampere, Finland.
Nieminen, T., Univ Helsinki, Dept Internal Med, Helsinki, Finland.
Nikus, K., Tampere Univ Hosp, Heart Ctr, Tampere, Finland.
Lehtimaki, T., Univ Tampere, Dept Clin Chem, Fimlab Labs, Tampere, Finland.
Viik, J., Tampere Univ Technol, BioMediTech Inst, Tampere, Finland.
Viik, J., Tampere Univ Technol, Fac Biomed Sci & Engn, Tampere, Finland.